UPSC CMS Pediatrics - Pediatric Nephrology & Genitourinary Disorders
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A diagnosis of steroid-dependent nephrotic syndrome is made in a 5-year-old male child, and he is initiated on a drug. After 6 weeks of therapy, he develops nausea, vomiting, neutropenia, and gross hematuria. Which of the following is the most likely drug used?
Cyclophosphamide
Levamisole
Cyclosporine
Prednisolone
A one-year-old male child presents with poor urinary stream and dribbling of urine since birth. A palpable mass is just above the symphysis pubis. The most likely diagnosis is:
Tumor of the urinary bladder
Posterior urethral valve
Ureterocele
Neuroblastoma
A five year old child was diagnosed with nephrotic syndrome, 18 months back. He was treated and successfully went into remission at that time. Following the initial episode, the child has had 3 relapses, each of which was successfully treated with oral prednisolone (60mg/m2/ 24h) until remission, followed by 40mg/m2 single dose, alternate days for four weeks. What is the diagnosis?
Nephrotic syndrome, infrequent relapses
Nephrotic syndrome, frequent relapses
Nephrotic syndrome, steroid dependent
Nephrotic syndrome, steroid resistant
A 6-year-old child presents with oliguria, hematuria, puffiness of face, convulsions, B.P. of 200/100 mm Hg and blood urea 80 mg%. What is the most likely diagnosis?
Hemolytic uremic syndrome
Nephrotic syndrome
Acute glomerulonephritis with hypertensive encephalopathy
Obstructive uropathy