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UPSC CMS Surgery - Endocrine Surgery

Attempt UPSC CMS Surgery - Endocrine Surgery under real exam conditions. Features timed computer-based test interface, textbook explanations, and detailed subject rank analytics.

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Real CBT Simulator Grid & Percentile
Duration
10 Mins
Countdown timer with review palette.
Marking Scheme
+4.00 / -1.00
Exact negative marking as per official exam rules.
Textbook Citations
Harrison & Bailey
Standard medical textbook solution references.
Target Exam
UPSC CMS
Official paper pattern & syllabus coverage.

📝 Sample Question Preview from UPSC CMS Surgery - Endocrine Surgery

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Question 1
A 45-year-old female presents with recurrent episodes of nephrolithiasis, generalized bone pain, and fatigue. Biochemical evaluation reveals hypercalcemia and elevated parathyroid hormone (PTH) levels. She undergoes parathyroidectomy. Postoperatively, she develops carpopedal spasms, perioral paresthesia, and a positive Chvostek sign. Which of the following statements regarding her immediate postoperative management is CORRECT?
A. Oral calcium and Vitamin D supplementation should be initiated only if symptoms persist beyond 48 hours.
B. Intravenous calcium gluconate is the most appropriate initial treatment for symptomatic hypocalcemia.
C. Serum phosphate levels should be aggressively lowered using phosphate binders to prevent calcium-phosphate deposition.
D. Magnesium supplementation is contraindicated as it can exacerbate hypocalcemia.
Textbook Explanation Highlight:
The patient is presenting with symptoms of acute hypocalcemia (carpopedal spasms, perioral paresthesia, positive Chvostek sign) following parathyroidectomy, likely due to 'hungry bone syndrome' or inadvertent parathyroid gland removal. Intravenous ca...
Question 2
Which of the following statements regarding the surgical management of medullary thyroid carcinoma (MTC) is INCORRECT?
A. Prophylactic total thyroidectomy is recommended for asymptomatic carriers of germline RET mutations, particularly those with RET codon M918T.
B. Serum calcitonin and carcinoembryonic antigen (CEA) levels are crucial for monitoring disease recurrence post-thyroidectomy.
C. Central neck dissection is indicated for all MTC patients, irrespective of clinical or radiological evidence of nodal involvement.
D. Patients with sporadic MTC should be screened for pheochromocytoma and primary hyperparathyroidism preoperatively.
Textbook Explanation Highlight:
Central neck dissection (CND) is generally indicated for all MTC patients due to the high incidence of central compartment lymph node metastases. However, for well-differentiated thyroid cancers, while it's often performed, the statement that it's in...
Question 3
A 55-year-old male presents with new-onset diabetes mellitus, migratory necrolytic erythema, and weight loss. Imaging reveals a pancreatic tail mass. Biopsy confirms a glucagonoma. Which of the following interventions is CONTRADICTED as an initial management strategy?
A. Administration of somatostatin analogs (e.g., octreotide) to control symptoms.
B. Surgical resection of the pancreatic tumor if resectable.
C. Aggressive insulin therapy to manage hyperglycemia before tumor localization.
D. Nutritional support with high-protein supplements.
Textbook Explanation Highlight:
Glucagonomas cause diabetes due to excessive glucagon production, which leads to hyperglycemia. The primary approach to managing the hyperglycemia in a glucagonoma patient is to address the underlying tumor (surgical resection if possible) and the ef...
Question 4
A 30-year-old female is diagnosed with a 3 cm solitary adrenal mass incidentally found on abdominal imaging for unrelated symptoms. Endocrine workup reveals normal serum cortisol, aldosterone, and catecholamine levels. The mass has benign imaging characteristics (low Hounsfield units, rapid contrast washout). She expresses concern about potential malignancy and requests surgical removal. What is the most appropriate management approach?
A. Adrenalectomy due to the patient's anxiety and the possibility of occult malignancy, regardless of size or function.
B. Repeat imaging in 6-12 months and biochemical re-evaluation, given the non-functional nature and benign imaging features.
C. Initiate empiric α-blockade and β-blockade to prevent hypertensive crisis during future surgery.
D. Recommend genetic testing for multiple endocrine neoplasia type 1 (MEN1).
Textbook Explanation Highlight:
This patient has an adrenal incidentaloma that is non-functional based on normal endocrine workup, and benign based on imaging characteristics (low Hounsfield units, rapid contrast washout are classic for benign adenomas). For such masses less than 4...
Question 5
Which of the following is characteristic of pheochromocytoma and its surgical management?
A. The 'rule of 10s' states that 10% are malignant, 10% are extra-adrenal, 10% are bilateral, and 10% are asymptomatic.
B. Preoperative alpha-adrenergic blockade should be initiated only if the patient is symptomatic with hypertension.
C. Laparoscopic adrenalectomy is contraindicated for all pheochromocytomas due to the risk of catecholamine release.
D. Measurement of plasma free metanephrines and normetanephrines is the least sensitive diagnostic test.
Textbook Explanation Highlight:
The 'rule of 10s' is a classic mnemonic for pheochromocytoma characteristics: 10% malignant, 10% extra-adrenal, 10% bilateral, 10% familial, 10% pediatric, and 10% present as an incidentaloma (asymptomatic). Preoperative alpha-adrenergic blockade is...
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